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Noninvasive Measurement of Protein Aggregation by Mutant Huntingtin Fragments or α-Synuclein in the Lens

Many diverse human diseases are associated with protein aggregation in ordered fibrillar structures called amyloid. Amyloid formation may mediate aberrant protein interactions that culminate in neurodegeneration in Alzheimer, Huntington, and Parkinson diseases and in prion encephalopathies. Studies...

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Detalhes bibliográficos
Main Authors: Muchowski, Paul J., Ramsden, Richard, Nguyen, QuangVu, Arnett, Ernest E., Greiling, Teri M., Anderson, Susan K., Clark, John I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650484/
https://ncbi.nlm.nih.gov/pubmed/18167346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709678200
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