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Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis
Glioblastoma multiforme (GBM) is a highly lethal brain tumor for which little treatment is available. The epidermal growth factor receptor (EGFR) signaling pathway is thought to play a crucial role in GBM pathogenesis, initiating the early stages of tumor development, sustaining tumor growth, promot...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650331/ https://ncbi.nlm.nih.gov/pubmed/19196966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813314106 |
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