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Blocking TGF-β–Smad2/3 innate immune signaling mitigates Alzheimer-like pathology
Alzheimer's disease is the most common dementia and is pathologically characterized by deposition of amyloid-β peptide (Aβ) into β-amyloid plaques, neuronal injury and low-level, chronic activation of brain immunity1. Transforming growth factor-βs (TGF-βs) are pleiotropic cytokines that have ke...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2649699/ https://ncbi.nlm.nih.gov/pubmed/18516051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1781 |
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