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TGF-β signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis
One unresolved issue in immune tolerance is what prevents self-reactive T cells from activation. In this study, we used a transgenic mouse model of targeted functional inactivation of TGF-βR signaling in CD11c(+) cells (CD11c(dnR) mice) and showed a direct impact on the development of experimental a...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2504840/ https://ncbi.nlm.nih.gov/pubmed/18669656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805058105 |
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