TGF-β signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis

One unresolved issue in immune tolerance is what prevents self-reactive T cells from activation. In this study, we used a transgenic mouse model of targeted functional inactivation of TGF-βR signaling in CD11c(+) cells (CD11c(dnR) mice) and showed a direct impact on the development of experimental a...

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Detaylı Bibliyografya
Asıl Yazarlar: Laouar, Yasmina, Town, Terrence, Jeng, David, Tran, Elise, Wan, Yisong, Kuchroo, Vijay K., Flavell, Richard A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2008
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504840/
https://ncbi.nlm.nih.gov/pubmed/18669656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805058105
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