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Il10 deficiency re-balances innate immunity to mitigate Alzheimer-like pathology
The impact of inflammation suppressor pathways on Alzheimer’s disease (AD) evolution remains poorly understood. Human evidence suggests involvement of the cardinal anti-inflammatory cytokine, interleukin-10 (Il10). We crossed the APP/PS1 mouse model of cerebral amyloidosis with a mouse deficient in...
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| Publicado no: | Neuron |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4352138/ https://ncbi.nlm.nih.gov/pubmed/25619654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.12.068 |
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