Expansion of the human μ-opioid receptor gene architecture: novel functional variants

The μ-opioid receptor (OPRM1) is the principal receptor target for both endogenous and exogenous opioid analgesics. There are substantial individual differences in human responses to painful stimuli and to opiate drugs that are attributed to genetic variations in OPRM1. In searching for new function...

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Hlavní autoři: Shabalina, Svetlana A., Zaykin, Dmitri V., Gris, Pavel, Ogurtsov, Aleksey Y., Gauthier, Josee, Shibata, Kyoko, Tchivileva, Inna E., Belfer, Inna, Mishra, Bikashkumar, Kiselycznyk, Carly, Wallace, Margaret R., Staud, Roland, Spiridonov, Nikolay A., Max, Mitchell B., Goldman, David, Fillingim, Roger B., Maixner, William, Diatchenko, Luda
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649019/
https://ncbi.nlm.nih.gov/pubmed/19103668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn439
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