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Expansion of the human μ-opioid receptor gene architecture: novel functional variants

The μ-opioid receptor (OPRM1) is the principal receptor target for both endogenous and exogenous opioid analgesics. There are substantial individual differences in human responses to painful stimuli and to opiate drugs that are attributed to genetic variations in OPRM1. In searching for new function...

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Detalhes bibliográficos
Main Authors: Shabalina, Svetlana A., Zaykin, Dmitri V., Gris, Pavel, Ogurtsov, Aleksey Y., Gauthier, Josee, Shibata, Kyoko, Tchivileva, Inna E., Belfer, Inna, Mishra, Bikashkumar, Kiselycznyk, Carly, Wallace, Margaret R., Staud, Roland, Spiridonov, Nikolay A., Max, Mitchell B., Goldman, David, Fillingim, Roger B., Maixner, William, Diatchenko, Luda
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649019/
https://ncbi.nlm.nih.gov/pubmed/19103668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn439
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