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Expansion of the human μ-opioid receptor gene architecture: novel functional variants

The μ-opioid receptor (OPRM1) is the principal receptor target for both endogenous and exogenous opioid analgesics. There are substantial individual differences in human responses to painful stimuli and to opiate drugs that are attributed to genetic variations in OPRM1. In searching for new function...

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Autori principali: Shabalina, Svetlana A., Zaykin, Dmitri V., Gris, Pavel, Ogurtsov, Aleksey Y., Gauthier, Josee, Shibata, Kyoko, Tchivileva, Inna E., Belfer, Inna, Mishra, Bikashkumar, Kiselycznyk, Carly, Wallace, Margaret R., Staud, Roland, Spiridonov, Nikolay A., Max, Mitchell B., Goldman, David, Fillingim, Roger B., Maixner, William, Diatchenko, Luda
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649019/
https://ncbi.nlm.nih.gov/pubmed/19103668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn439
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