The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest

DNA damage induced by ionizing radiation (IR) activates p53, leading to the regulation of downstream pathways that control cell-cycle progression and apoptosis. However, the mechanisms for the IR-induced p53 activation and the differential activation of pathways downstream of p53 are unclear. Here w...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Sa, Guo, Min, Ouyang, Honghai, Li, Xiaoling, Cordon-Cardo, Carlos, Kurimasa, Akihiro, Chen, David J., Fuks, Zvi, Ling, C. Clifton, Li, Gloria C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2000
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC26478/
https://ncbi.nlm.nih.gov/pubmed/10677503
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