The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest

DNA damage induced by ionizing radiation (IR) activates p53, leading to the regulation of downstream pathways that control cell-cycle progression and apoptosis. However, the mechanisms for the IR-induced p53 activation and the differential activation of pathways downstream of p53 are unclear. Here w...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wang, Sa, Guo, Min, Ouyang, Honghai, Li, Xiaoling, Cordon-Cardo, Carlos, Kurimasa, Akihiro, Chen, David J., Fuks, Zvi, Ling, C. Clifton, Li, Gloria C.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26478/
https://ncbi.nlm.nih.gov/pubmed/10677503
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados