High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients

Transforming mutations in NRAS and KRAS are thought to play a causative role in the development of numerous cancers, including myeloid malignancies. Although mutations at amino acids 12, 13, or 61 account for the majority of oncogenic Ras variants, we hypothesized that less frequent mutations at alt...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Tyner, Jeffrey W., Erickson, Heidi, Deininger, Michael W. N., Willis, Stephanie G., Eide, Christopher A., Levine, Ross L., Heinrich, Michael C., Gattermann, Norbert, Gilliland, D. Gary, Druker, Brian J., Loriaux, Marc M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2009
Fag:
Myeloid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647674/
https://ncbi.nlm.nih.gov/pubmed/19075190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-04-152157
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker