Učitavanje...
Identification of Adducts Formed in the Reactions of 5′-Acetoxy-N′-nitrosonornicotine with Deoxyadenosine, Thymidine, and DNA
N′-Nitrosonornicotine (NNN) is the most prevalent of the carcinogenic tobacco-specific nitrosamines found in all tobacco products. Previous studies have demonstrated that cytochrome-P450 mediated 5′-hydroxylation of NNN is a major metabolic pathway leading to mutagenic products, but to date DNA addu...
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| Glavni autori: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646895/ https://ncbi.nlm.nih.gov/pubmed/18821782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx8002559 |
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