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Evaluating a surrogate endpoint at three levels, with application to vaccine development

Identification of an immune response to vaccination that reliably predicts protection from clinically significant infection, i.e. an immunological surrogate endpoint, is a primary goal of vaccine research. Using this problem of evaluating an immunological surrogate as an illustration, we describe a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gilbert, Peter B., Qin, Li, Self, Steven G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646675/
https://ncbi.nlm.nih.gov/pubmed/17979212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3122
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