Llwytho...

Statistical identifiability and the surrogate endpoint problem, with application to vaccine trials

Given a randomized treatment Z, a clinical outcome Y, and a biomarker S measured some fixed time after Z is administered, we may be interested in addressing the surrogate endpoint problem by evaluating whether S can be used to reliably predict the effect of Z on Y. Several recent proposals for the s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wolfson, Julian, Gilbert, Peter
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597127/
https://ncbi.nlm.nih.gov/pubmed/20105158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2009.01380.x
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