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Reduced expression of A-type lamins and emerin activates extracellular signal-regulated kinase in cultured cells

BACKGROUND: Mutations in genes encoding A-type lamins and emerin cause cardiomyopathy and muscular dystrophy. We previously showed activation of the extracellular signal-regulated kinase (ERK) branch of the mitogen-activated protein kinase (MAPK) cascade in hearts of mice with mutations in these gen...

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Bibliografische gegevens
Hoofdauteurs: Muchir, Antoine, Wu, Wei, Worman, Howard J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646592/
https://ncbi.nlm.nih.gov/pubmed/19022376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2008.10.012
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