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Targeting Mitogen-Activated Protein Kinase Signaling in Mouse Models of Cardiomyopathy Caused by Lamin A/C Gene Mutations

The most frequently occurring mutations in the gene encoding nuclear lamin A and nuclear lamin C cause striated muscle diseases virtually always involving the heart. In this review, we describe the approaches and methods used to discover that cardiomyopathy-causing lamin A/C gene mutations increase...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Muchir, Antoine, Worman, Howard J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878678/
https://ncbi.nlm.nih.gov/pubmed/26795484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2015.07.028
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