Abnormal p38α mitogen-activated protein kinase signaling in dilated cardiomyopathy caused by lamin A/C gene mutation

We previously interrogated the transcriptome in heart tissue from Lmna(H222P/H222P) mice, a mouse model of cardiomyopathy caused by lamin A/C gene (LMNA) mutation, and found that the extracellular signal-regulated kinase 1/2 and Jun N-terminal kinase branches of the mitogen-activated protein (MAP) k...

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Bibliographic Details
Main Authors: Muchir, Antoine, Wu, Wei, Choi, Jason C., Iwata, Shinichi, Morrow, John, Homma, Shunichi, Worman, Howard J.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441127/
https://ncbi.nlm.nih.gov/pubmed/22773734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds265
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