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Reduced expression of A-type lamins and emerin activates extracellular signal-regulated kinase in cultured cells
BACKGROUND: Mutations in genes encoding A-type lamins and emerin cause cardiomyopathy and muscular dystrophy. We previously showed activation of the extracellular signal-regulated kinase (ERK) branch of the mitogen-activated protein kinase (MAPK) cascade in hearts of mice with mutations in these gen...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646592/ https://ncbi.nlm.nih.gov/pubmed/19022376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2008.10.012 |
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