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TNF-α stimulation inhibits siRNA-mediated RNA interference through a mechanism involving poly-(A) tail stabilization

The control of mRNA stability is a complex biological process that involves numerous factors, including microRNA (miRNA) and short interfering RNA (siRNA). Here, we show that short interfering RNA (siRNA) and microRNA share some similarities in their response to cellular stress. miR16 expedites the...

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Detalhes bibliográficos
Main Authors: Mols, Johann, van den Berg, Arjen, Otsuka, Motoyuki, Zheng, Min, Chen, Jianming, Han, Jiahuai
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646504/
https://ncbi.nlm.nih.gov/pubmed/18423387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2008.03.007
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