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Terminal Duplex Stability and Nucleotide Identity Differentially Control siRNA Loading and Activity in RNA Interference
Efficient short interfering RNA (siRNA)-mediated gene silencing requires selection of a sequence that is complementary to the intended target and possesses sequence and structural features that encourage favorable functional interactions with the RNA interference (RNAi) pathway proteins. In this stu...
Shranjeno v:
| izdano v: | Nucleic Acid Ther |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Mary Ann Liebert, Inc.
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5067871/ https://ncbi.nlm.nih.gov/pubmed/27399870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2016.0612 |
| Oznake: |
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