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Thermal Stability of siRNA Modulates Aptamer- conjugated siRNA Inhibition
Oligonucleotide aptamer-mediated in vivo cell targeting of small interfering RNAs (siRNAs) is emerging as a useful approach to enhance the efficacy and reduce the adverse effects resulting from siRNA-mediated genetic interference. A current main impediment in aptamer-mediated siRNA targeting is that...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499696/ https://ncbi.nlm.nih.gov/pubmed/23344651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2012.41 |
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