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Dual inhibition of PI3Kα and mTOR as an alternative treatment for Kaposi's sarcoma

Rapamycin (or sirolimus), the prototypical inhibitor of the mammalian target of rapamycin (mTOR) and an immunosuppressant used for the prevention of renal transplant rejection, has recently emerged as an effective treatment for Kaposi's sarcoma (KS), an enigmatic vascular tumor and a model for...

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Autors principals: Chaisuparat, Risa, Hu, Jiadi, Jham, Bruno C., Knight, Zachary A., Shokat, Kevan M., Montaner, Silvia
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645787/
https://ncbi.nlm.nih.gov/pubmed/18922908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0878
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