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Dual inhibition of PI3Kα and mTOR as an alternative treatment for Kaposi's sarcoma

Rapamycin (or sirolimus), the prototypical inhibitor of the mammalian target of rapamycin (mTOR) and an immunosuppressant used for the prevention of renal transplant rejection, has recently emerged as an effective treatment for Kaposi's sarcoma (KS), an enigmatic vascular tumor and a model for...

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Détails bibliographiques
Auteurs principaux: Chaisuparat, Risa, Hu, Jiadi, Jham, Bruno C., Knight, Zachary A., Shokat, Kevan M., Montaner, Silvia
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645787/
https://ncbi.nlm.nih.gov/pubmed/18922908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0878
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