Llwytho...

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

The PI3 kinase family of lipid kinases promotes cell growth and survival by generating the second messenger phosphatidylinositol-3,4,5-trisphosphate. To define targets critical for cancers driven by activation of PI3 kinase, we screened a panel of potent and structurally diverse drug-like molecules...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fan, Qi-Wen, Knight, Zachary A., Goldenberg, David D., Yu, Wei, Mostov, Keith E., Stokoe, David, Shokat, Kevan M., Weiss, William A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925230/
https://ncbi.nlm.nih.gov/pubmed/16697955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2006.03.029
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