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A structural model of latent evolutionary potentials underlying neutral networks in proteins

A central question in molecular evolution concerns the nature of phenotypic transitions, in particular, if neutral mutations hamper or somehow facilitate adaptability of proteins to new requirements. Proteins have been found to fluctuate between different structures, with frequencies of structures b...

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Detalhes bibliográficos
Main Authors: Wroe, Richard, Chan, Hue Sun, Bornberg-Bauer, Erich
Formato: Artigo
Idioma:Inglês
Publicado em: HFSP Publishing 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645552/
https://ncbi.nlm.nih.gov/pubmed/19404462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2976/1.2739116
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