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Latent evolutionary potentials under the neutral mutational drift of an enzyme

Biological systems exhibit mutational robustness, or neutrality, whereby the impact of mutations is minimized. Does neutrality hamper their ability to adapt in the face of changing environments? We monitored changes in genotype and phenotype that occur within a neutral mutational network of an enzym...

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Detalhes bibliográficos
Main Authors: Amitai, Gil, Gupta, Rinkoo Devi, Tawfik, Dan S.
Formato: Artigo
Idioma:Inglês
Publicado em: HFSP Publishing 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645560/
https://ncbi.nlm.nih.gov/pubmed/19404461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2976/1.2739115
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