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Modulation of Cell Migration and Invasiveness by Tumor Suppressor TSC2 in Lymphangioleiomyomatosis

The loss of TSC2 function is associated with the pathobiology of lymphangioleiomyomatosis (LAM), which is characterized by the abnormal proliferation, migration, and differentiation of smooth muscle–like cells within the lungs. Although the etiology of LAM remains unknown, clinical and genetic evide...

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Autores principales: Goncharova, Elena A., Goncharov, Dmitriy A., Lim, Poay N., Noonan, Daniel, Krymskaya, Vera P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644208/
https://ncbi.nlm.nih.gov/pubmed/16388022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0374OC
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