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Abnormal Growth of Smooth Muscle–Like Cells in Lymphangioleiomyomatosis: Role for Tumor Suppressor TSC2
The TSC1 and TSC2 proteins, which function as a TSC1/TSC2 tumor suppressor complex, are associated with lymphangioleiomyomatosis (LAM), a genetic disorder characterized by the abnormal growth of smooth muscle–like cells in the lungs. The precise molecular mechanisms that modulate LAM cell growth rem...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Thoracic Society
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2644221/ https://ncbi.nlm.nih.gov/pubmed/16424383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0300OC |
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