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Abnormal Growth of Smooth Muscle–Like Cells in Lymphangioleiomyomatosis: Role for Tumor Suppressor TSC2

The TSC1 and TSC2 proteins, which function as a TSC1/TSC2 tumor suppressor complex, are associated with lymphangioleiomyomatosis (LAM), a genetic disorder characterized by the abnormal growth of smooth muscle–like cells in the lungs. The precise molecular mechanisms that modulate LAM cell growth rem...

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Detalhes bibliográficos
Main Authors: Goncharova, Elena A., Goncharov, Dmitriy A., Spaits, Matthew, Noonan, Daniel J., Talovskaya, Ekaterina, Eszterhas, Andrew, Krymskaya, Vera P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644221/
https://ncbi.nlm.nih.gov/pubmed/16424383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0300OC
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