Abnormal Growth of Smooth Muscle–Like Cells in Lymphangioleiomyomatosis: Role for Tumor Suppressor TSC2

The TSC1 and TSC2 proteins, which function as a TSC1/TSC2 tumor suppressor complex, are associated with lymphangioleiomyomatosis (LAM), a genetic disorder characterized by the abnormal growth of smooth muscle–like cells in the lungs. The precise molecular mechanisms that modulate LAM cell growth rem...

Full description

Saved in:
Bibliographic Details
Main Authors: Goncharova, Elena A., Goncharov, Dmitriy A., Spaits, Matthew, Noonan, Daniel J., Talovskaya, Ekaterina, Eszterhas, Andrew, Krymskaya, Vera P.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2006
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644221/
https://ncbi.nlm.nih.gov/pubmed/16424383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0300OC
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items