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Chemokine-Enhanced Chemotaxis of Lymphangioleiomyomatosis Cells with Mutations in the Tumor Suppressor TSC2 Gene

Lymphangioleiomyomatosis (LAM) is characterized by cystic lung destruction caused by LAM cells (smooth-muscle-like cells) that have mutations in the tumor suppressor genes tuberous sclerosis complex (TSC) 1 or 2 and have the capacity to metastasize. Since chemokines and their receptors function in c...

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Detalhes bibliográficos
Main Authors: Pacheco-Rodriguez, Gustavo, Kumaki, Fumiyuki, Steagall, Wendy K., Zhang, Yi, Ikeda, Yoshihiko, Lin, Jing-Ping, Billings, Eric M., Moss, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947111/
https://ncbi.nlm.nih.gov/pubmed/19155472
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