Erythropoietin-driven proliferation of cells with mutations in the tumor suppressor gene TSC2

Lymphangioleiomyomatosis (LAM) is characterized by cystic lung destruction, resulting from proliferation of smooth-muscle-like cells, which have mutations in the tumor suppressor genes TSC1 or TSC2. Among 277 LAM patients, severe disease was associated with hypoxia and elevated red blood cell indexe...

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Detalhes bibliográficos
Main Authors: Ikeda, Yoshihiko, Taveira-DaSilva, Angelo M., Pacheco-Rodriguez, Gustavo, Steagall, Wendy K., El-Chemaly, Souheil, Gochuico, Bernadette R., May, Rose M., Hathaway, Olanda M., Li, Shaowei, Wang, Ji-an, Darling, Thomas N., Stylianou, Mario, Moss, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023287/
https://ncbi.nlm.nih.gov/pubmed/21036916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00095.2010
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