Lymphangioleiomyomatosis (LAM): Molecular insights lead to targeted therapies

LAM is a rare lung disease, found primarily in women of childbearing age, characterized by cystic lung destruction and abdominal tumors (e.g., renal angiomyolipoma, lymphangioleiomyoma). The disease results from proliferation of a neoplastic cell, termed the LAM cell, which has mutations in either o...

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Main Authors: Glasgow, Connie G., Steagall, Wendy K., Taveira-DaSilva, Angelo, Pacheco-Rodriguez, Gustavo, Cai, Xiong, El-Chemaly, Souheil, Moses, Marsha, Darling, Thomas, Moss, Joel
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030250/
https://ncbi.nlm.nih.gov/pubmed/20630348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.rmed.2010.03.017
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