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Chronic NF-κB blockade reduces cytosolic and mitochondrial oxidative stress and attenuates renal injury and hypertension in SHR
Nuclear factor-κB (NF-κB) plays an important role in hypertensive renal injury; however, its roles in perpetuating mitochondrial oxidative stress and renal dysfunction remain unclear. In this study, we assessed the effects of chronic NF-κB blockade with pyrrolidine dithiocarbamate (PDTC) on renal dy...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643866/ https://ncbi.nlm.nih.gov/pubmed/19073636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90628.2008 |
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