HDAC Inhibition Attenuates Inflammatory, Hypertrophic and Hypertensive Responses in Spontaneously Hypertensive Rats

Reactive oxygen species and pro-inflammatory cytokines contribute to cardiovascular diseases. Inhibition of downstream transcription factors and gene modifiers of these components are key mediators of hypertensive response. Histone acetylases/deacetylases can modulate the gene expression of these hy...

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Bibliographic Details
Main Authors: Cardinale, Jeffrey P, Sriramula, Srinivas, Pariaut, Romain, Guggilam, Anuradha, Mariappan, Nithya, Elks, Carrie, Francis, Joseph
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931819/
https://ncbi.nlm.nih.gov/pubmed/20679181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.110.154567
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