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Central TNF inhibition results in attenuated neurohumoral excitation in heart failure: a role for superoxide and nitric oxide

This study examined the effect of central tumor necrosis factor-alpha (TNF) blockade on the imbalance between nitric oxide and superoxide production in the paraventricular nucleus (PVN) and ventrolateral medulla (VLM), key autonomic regulators, and their contribution to enhanced sympathetic drive in...

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Bibliographic Details
Main Authors: Guggilam, Anuradha, Cardinale, Jeffrey P., Mariappan, Nithya, Sriramula, Srinivas, Haque, Masudul, Francis, Joseph
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261085/
https://ncbi.nlm.nih.gov/pubmed/21246206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-010-0146-8
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