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Diet-induced Renal Changes in Zucker Rats Are Ameliorated by the Superoxide Dismutase Mimetic TEMPOL

Diabetic nephropathy is the leading cause of renal failure in the United States. The obese Zucker rat (OZR; fa/fa) is a commonly used model of type 2 diabetes and metabolic syndrome (MetS), and of the nephropathy and renal oxidative stress commonly seen in these disorders. Heterozygous lean Zucker r...

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Detalhes bibliográficos
Main Authors: Ebenezer, Philip J., Mariappan, Nithya, Elks, Carrie, Haque, Masudul, Francis, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784093/
https://ncbi.nlm.nih.gov/pubmed/19424163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2009.137
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