Tempol, a Superoxide Dismutase Mimetic Agent, Ameliorates Cisplatin-Induced Nephrotoxicity through Alleviation of Mitochondrial Dysfunction in Mice

BACKGROUND: Mitochondrial dysfunction is a crucial mechanism by which cisplatin, a potent chemotherapeutic agent, causes nephrotoxicity where mitochondrial electron transport complexes are shifted mostly toward imbalanced reactive oxygen species versus energy production. In the present study, the pr...

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Detaylı Bibliyografya
Asıl Yazarlar: Ahmed, Lamiaa A., Shehata, Nagwa I., Abdelkader, Noha F., Khattab, Mahmoud M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182751/
https://ncbi.nlm.nih.gov/pubmed/25271439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108889
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