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Diet-induced Renal Changes in Zucker Rats Are Ameliorated by the Superoxide Dismutase Mimetic TEMPOL

Diabetic nephropathy is the leading cause of renal failure in the United States. The obese Zucker rat (OZR; fa/fa) is a commonly used model of type 2 diabetes and metabolic syndrome (MetS), and of the nephropathy and renal oxidative stress commonly seen in these disorders. Heterozygous lean Zucker r...

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Détails bibliographiques
Auteurs principaux: Ebenezer, Philip J., Mariappan, Nithya, Elks, Carrie, Haque, Masudul, Francis, Joseph
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784093/
https://ncbi.nlm.nih.gov/pubmed/19424163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2009.137
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