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RIAM Activates Integrins by Linking Talin to Ras GTPase Membrane-targeting Sequences
Rap1 small GTPases interact with Rap1-GTP-interacting adaptor molecule (RIAM), a member of the MRL (Mig-10/RIAM/Lamellipodin) protein family, to promote talin-dependent integrin activation. Here, we show that MRL proteins function as scaffolds that connect the membrane targeting sequences in Ras GTP...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643525/ https://ncbi.nlm.nih.gov/pubmed/19098287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807117200 |
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