Conformational activation of talin by RIAM triggers integrin-mediated cell adhesion

The membrane localization and activation of cytoskeletal protein talin are key steps to initiate integrin transmembrane receptors activation, which mediates many cellular adhesive responses such as cell migration, spreading, and proliferation. RIAM, a membrane anchor and small GTPase RAP1 effector,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Yang, Jun, Zhu, Liang, Zhang, Hao, Hirbawi, Jamila, Fukuda, Koichi, Dwivedi, Pallavi, Liu, Jianmin, Byzova, Tatiana, Plow, Edward F., Wu, Jinhua, Qin, Jun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432866/
https://ncbi.nlm.nih.gov/pubmed/25520155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6880
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