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5′-O-D-VALYL ara A, A POTENTIAL PRODRUG FOR IMPROVING ORAL BIOAVAILABILITY OF THE ANTIVIRAL AGENT VIDARABINE

In order to improve the oral bioavailability of Adenine 9-β-D-arabinofuranoside (Vidarabine, also called ara A), an antiviral drug which is active against herpes simplex and varicella zoster viruses and the first agent to be licensed for the treatment of systematic herpes virus infection in man, the...

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Detalles Bibliográficos
Main Authors: Shen, Wei, Kim, Jae-Seung, Mitchell, Stefanie, Kish, Phil, Kijek, Paul, Hilfinger, John
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642978/
https://ncbi.nlm.nih.gov/pubmed/19116869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15257770802581757
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