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An Orally Bioavailable (Mice) Prodrug of Glutathione

L-Cysteine-glutathione mixed disulfide (CySSG), a prodrug of glutathione (GSH), was found to be orally bioavailable in mice, and protected mice against a toxic dose of acetaminophen. If oral bioavailability can also be demonstrated in humans, a wide range of applicability for CySSG can be envisioned...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antioxidants (Basel)
Egile Nagusiak: Crankshaw, Daune L., Briggs, Jacquie E., Vince, Robert, Nagasawa, Herbert T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8226670/
https://ncbi.nlm.nih.gov/pubmed/34200599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10060939
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