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Receptor-mediated phagocytosis elicits cross-presentation in nonprofessional antigen-presenting cells

In cross-presentation by dendritic cells (DCs), internalized proteins are retrotranslocated into the cytosol, degraded by the proteasome, and the generated antigenic peptides bind to MHC class I molecules for presentation on the cell surface. Endoplasmic reticulum (ER) contribution to phagosomal mem...

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Detalhes bibliográficos
Main Authors: Giodini, Alessandra, Rahner, Christoph, Cresswell, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642664/
https://ncbi.nlm.nih.gov/pubmed/19218463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813305106
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