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Proteasomal degradation within endocytic organelles mediates antigen cross‐presentation
During MHC‐I‐restricted antigen processing, peptides generated by cytosolic proteasomes are translocated by the transporter associated with antigen processing (TAP) into the endoplasmic reticulum, where they bind to newly synthesized MHC‐I molecules. Dendritic cells and other cell types can also gen...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6694219/ https://ncbi.nlm.nih.gov/pubmed/31271236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899266 |
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