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Defective cross-presentation of viral antigens in GILT-free mice
Gamma-Interferon-inducible Lysosomal Thiolreductase (GILT) promotes Major Histocompatibility Complex (MHC) class II-restricted presentation of exogenous antigens containing disulfide bonds. Here we show that GILT also facilitates MHC class I-restricted recognition of such antigens by CD8(+) T cells,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2925227/ https://ncbi.nlm.nih.gov/pubmed/20538950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1189176 |
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