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Hsp90-mediated cytosolic refolding of exogenous proteins internalized by dendritic cells
Dendritic cells efficiently internalize exogenous protein antigens by fluid-phase uptake and receptor-mediated endocytosis. Such antigens contribute to cross-presentation by being translocated into the cytosol for proteasomal degradation, which liberates immunogenic peptides that can bind to major h...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2104710/ https://ncbi.nlm.nih.gov/pubmed/18046456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601941 |
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