Enhanced and prolonged cross-presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles

CD8(+) T-cell responses are critical in the immunological control of tumours and infectious diseases. To prime CD8(+) T cells against these cell-associated antigens, exogenous antigens must be cross-presented by professional antigen-presenting cells (APCs). While cross-presentation of soluble antige...

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Detalhes bibliográficos
Main Authors: Shen, Hong, Ackerman, Anne L, Cody, Virginia, Giodini, Alessandra, Hinson, Ella R, Cresswell, Peter, Edelson, Richard L, Saltzman, W Mark, Hanlon, Douglas J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782199/
https://ncbi.nlm.nih.gov/pubmed/16423043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2005.02268.x
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