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Coordination of Eukaryotic Translation Elongation Factor 1A (eEF1A) Function in Actin Organization and Translation Elongation by the Guanine Nucleotide Exchange Factor eEF1Bα

Eukaryotic translation elongation factor 1A (eEF1A) both shuttles aminoacyl-tRNA (aa-tRNA) to the ribosome and binds and bundles actin. A single domain of eEF1A is proposed to bind actin, aa-tRNA and the guanine nucleotide exchange factor eEF1Bα. We show that eEF1Bα has the ability to disrupt eEF1A-...

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Autors principals: Pittman, Yvette R., Kandl, Kimberly, Lewis, Marcus, Valente, Louis, Kinzy, Terri Goss
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640982/
https://ncbi.nlm.nih.gov/pubmed/19095653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807945200
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