Eukaryotic translation elongation factor 2 (eEF2) catalyzes reverse translocation of the eukaryotic ribosome

During protein synthesis, a ribosome moves along the mRNA template and, using aminoacyl-tRNAs, decodes the template nucleotide triplets to assemble a protein amino acid sequence. This movement is accompanied by shifting of mRNA–tRNA complexes within the ribosome in a process called translocation. In...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Susorov, Denis, Zakharov, Nikita, Shuvalova, Ekaterina, Ivanov, Alexander, Egorova, Tatiana, Shuvalov, Alexey, Shatsky, Ivan N., Alkalaeva, Elena
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2018
Subjects:
Protein Synthesis and Degradation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892567/
https://ncbi.nlm.nih.gov/pubmed/29453282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000761
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