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Phosphorylation of Eukaryotic Elongation Factor 2 (eEF2) by Cyclin A–Cyclin-Dependent Kinase 2 Regulates Its Inhibition by eEF2 Kinase

Protein synthesis is highly regulated via both initiation and elongation. One mechanism that inhibits elongation is phosphorylation of eukaryotic elongation factor 2 (eEF2) on threonine 56 (T56) by eEF2 kinase (eEF2K). T56 phosphorylation inactivates eEF2 and is the only known normal eEF2 functional...

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Bibliografiska uppgifter
Huvudupphovsmän: Hizli, Asli A., Chi, Yong, Swanger, Jherek, Carter, John H., Liao, Yi, Welcker, Markus, Ryazanov, Alexey G., Clurman, Bruce E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554216/
https://ncbi.nlm.nih.gov/pubmed/23184662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01270-12
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